Search results for: activities
Correlates of Protection
Role of Correlates of Protection, or Immune Measurements, in Predicting Protective Immunity of COVID-19 Vaccines March 29, 2021 Broadly speaking, correlates of protection are measurements of immune parameters that allow prediction of the degree of protection against infection or disease induced by a pathogen. A prime point of interest in consideration of protection against SARS-CoV-2…
Read MoreGLOBAL VIRUS NETWORK (GVN) ADDS SANOFI PASTEUR TO GVN HEALTHCARE & PHARMA CENTERS OF EXCELLENCE COALITION
The Partnership Focuses on Training The Next Generation of Virus Researchers to Safeguard Mankind from Current and Future Threats Baltimore, Maryland, USA, March 23, 2021: The Global Virus Network (“GVN”), the world’s leading coalition of virologists combatting current and emerging pandemic viral threats and viral causes of disease through international collaborative research response, by training…
Read MoreGVN Healthcare & Pharma Centers of Excellence Coalition
GVN Healthcare & Pharma Centers of Excellence Coalition GVN Healthcare & Pharma Centers of Excellence The business community is an integral partner in stemming the spread of viral diseases worldwide. Viral outbreaks, such as SARS-CoV-2 / COVID19, know no boundaries and spread rapidly beyond national borders, accompanied by panic, uncertainty, and losses to workforces, productivity…
Read MoreVariants of Interest
Eta (B.1.525) This variant was first detected in Nigeria and UK in December 2020. It has been seen in other countries, including U.S., Canada, Denmark, Britain, France, Belgium, Spain, Finland, Nigeria, Ghana, Jordan, Australia and Singapore. As of Feb. 17, 46 and 12 cases of the variant had been confirmed by gene sequencing in the…
Read MoreGamma (P.1)
Background The variant known as Gamma or P.1 was first detected in Brazil It has caused widespread infection in the city of Manaus. As shown with other UK and South African variants, the Brazilian variant has shown to enhanced transmissibility and is spreading globally. Notable mutations: N501Y, K417N, and E484K in the receptor binding domain…
Read MoreVaccine Overview
Vaccine Overview Vaccination can be the most efficient and effective measures in controlling the pandemics and save millions of lives. There are currently more than 60 COVID-19 vaccine candidates in clinical development and over 170 in pre-clinical development. The GVN is providing valuable information and resources for COVID-19 vaccines. Spike Protein of SARS-CoV-2 for Vaccine…
Read MoreCOVID-19 and Autoimmunity
COVID-19 and Autoimmunity Are Severe Cases of COVID-19 Related to an Autoimmune Disease? February 15, 2021 COVID-19, the disease caused by SARS-CoV-2, involves at least two distinct phases. The first phase is attributed to typical progress of respiratory disease by causing fever, cough, loss of taste/smell, and other symptoms typical of respiratory infections. The second…
Read MoreGVN Variants and Vaccine Resource Portal
Alpha (B.1.1.7) Beta (B.1.351) Gamma (P.1) Delta (B.1.617.2) GVN Experts Address What You Need to Know About Variants and Vaccines Vaccines Yes, although this is rare, since the current vaccines are effective against the Delta variant. Yet reinfections (i.e., breakthrough infections) can occur. The US CDC has recently evaluated breakthrough infections that cause hospitalization or…
Read MoreInterferon Antagonism of SARS-CoV-2
It has become clear that the type 1 interferon responses to SARS-CoV-2 have a great deal to do with the outcome of infection. Patients with benign courses of infection yield high levels of expression of interferon-α (IFNα), while critical cases of COVID-19 show low levels of its expression. Paradoxically, in severe disease, expression of INF…
Read MoreRapid and Frequent Testing for COVID-19
The cases of new SARS-CoV-2 infections are currently increasing at an alarming rate, suggesting that winter might bring a large healthcare crisis. Diagnostics have become a critical tool in curbing COVID-19. It is important that accurate results be obtained rapidly and that collection of samples be as fast, simple, and convenient as possible. What tests…
Read More