Vaccine Overview

Vaccine Overview

Vaccination can be the most efficient and effective measures in controlling the pandemics and save millions of lives. There are currently more than 60 COVID-19 vaccine candidates in clinical development and over 170 in pre-clinical development. The GVN is providing valuable information and resources for COVID-19 vaccines.

Spike Protein of SARS-CoV-2 for Vaccine Development

  • Spike (S) protein plays the most important roles in viral attachment, fusion, and entry.
  • Receptor binding domain (RBD) of the S protein binds to human ACE2 receptor.
  • RBD is a target for induction of neutralizing antibodies.
  • For current COVID-19 vaccine development, the spike protein is expressed by using various platforms to induce immune responses.

Available COVID-19 Vaccines

COVID-19 Vaccine Strategies

Sources for Vaccine Safety and Other Information