New Antivirals: Could They Be Game Changers?
November 1, 2021
There have been recent reports of potentially effective oral antiviral drugs, including RNA replicase and viral protease inhibitors. If these prove safe and effective, this may overhaul the care of patients with COVID-19 by preventing severe COVID-19 in infected patients and, possibly in the future, prevent infection after contamination. It is likely that combining antivirals with different mechanisms of action will be necessary, as for many other viral infections. On the other hand, they may have some negative impact on preventing COVID-19 by reducing protection measures and increasing vaccine hesitancy. Thus, whatever the efficacy of the direct antivirals against infection by SARS-CoV-2, vaccination will remain key. What are these drugs, how do they act, and how effective are they?