A compilation of GVN GVN Center/Member Academic Publications
Read the latest publications:
Detection of SARS-CoV-2 in Air and on Surfaces in Rooms of Infected Nursing Home Residents
Oxford Academic, September 7, 2022
SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesis
PNAS, August 30, 2022
Post-COVID-19 condition 3 months after hospitalisation with SARS-CoV-2 in South Africa: a prospective cohort study
The Lancet Global Health, September 1, 2022
Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil.
Nature Microbiology, August 18, 2022
Time to Stop Using Ineffective Covid-19 Drugs
NJEM, August 18, 2022
Asymptomatic Infection? Another Reason to Consider Monkeypox a Disease of Public Health Concern
Annals of Internal Medicine, August 16, 2022
Update on the Monkeypox Outbreak
JAMA Network, August 11, 2022
A Zoonotic Henipavirus in Febrile Patients in China
N Engl J Med, August 4, 2022
The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2
Science, July 26, 2022
The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic
Science, July, 26, 2022
Why does viral RNA sometimes persist after recovery from acute infections? – PMC (nih.gov)
PLoS Biology, June 2022
Use of Oral Polio Vaccine and the Global Incidence of Mother-to-Child Human Immunodeficiency Virus Transmission
Frontiers in Public Health, June 9, 2022
Dr. Farrokh Habibzadeh (GVN Middle East Region, Shiraz, Iran) et al.
Determining the SARS-CoV-2 serological immunoassay test performance indices based on the test results frequency distribution
Biochemia Medica, June 15, 2022
Dr. Farrokh Habibzadeh (GVN Middle East Region, Shiraz, Iran) et al.
The apparent prevalence, the true prevalence
Biochemia Medica, June 15, 2022
Dr. Farrokh Habibzadeh (GVN Middle East Region, Shiraz, Iran) et al.
Efficacy and Safety of the RBD-Dimer–Based Covid-19 Vaccine ZF2001 in Adults
June 2, 2022, N Engl J Med 2022; 386:2097-2111; DOI: 10.1056/NEJMoa2202261
Dr. Erkin Musabaev (Institute of Virology Tashkent, Uzbekistan) et al.
Omicron infection enhances Delta antibody immunity in vaccinated persons
Nature. 2022 doi: 10.1038/s41586-022-04830-x.
Dr. Penny Moore (NHLS Johannesburg National Institute for Communicable Diseases) et al.
B cell responses in hospitalized SARS-CoV-2-infected children with and without Multisystem Inflammatory SyndromeJ Infect Dis. 2022 doi: 10.1093/infdis/jiac119.
Dr. Diane Griffin (Johns Hopkins Bloomberg School of Public Health) et al.
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial
J Infect. 2022 Apr 9;S0163-4453(22)00200-6. doi: 10.1016/j.jinf.2022.04.018.
Dr. Emma Thomson (The MRC-University of Glasgow Centre for Virus Research, UK)
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions
Sci Transl Med. 2022 Mar 29;eabm2311. doi: 10.1126/scitranslmed.abm2311.
Drs. Erica Saphire (The Scripps Research Institute), Florian Krammer (Icahn School of Medicine at Mount Sinai) et al.
Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants
Cell. 2022 Mar 18;S0092-8674(22)00329-4. doi: 10.1016/j.cell.2022.03.019. Online ahead of print.
Dr. Melanie Ott (Gladstone Institute of Virology & Immunology) et al.
Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage
Nat Commun. 2022 Apr 8;13(1):1976. doi: 10.1038/s41467-022-29579-9.
Penny L Moore (The National Institute for Communicable Diseases, South Africa) et al.
Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model
Microorganisms. 2022 Mar 16;10(3):633. doi: 10.3390/microorganisms10030633.
Dr. Johan Neyts and colleagues (Rega Institute for Medical Research, Belgium)
The early SARS-CoV-2 epidemic in Senegal was driven by the local emergence of B.1.416 and the introduction of B.1.1.420 from Europe
Virus Evolution, Volume 8, Issue 1, 2022, veac025, https://doi.org/10.1093/ve/veac025.
Drs. Gavin A Cloherty (Abbott), Souleymane Mboup (IRESSEF laboratories, Senegal) et al.
Assessment of SARS-CoV-2 Mu Variant Emergence and Spread in Colombia
JAMA Netw Open. 2022 Mar 1;5(3):e224754. doi: 10.1001/jamanetworkopen.2022.4754.
Drs. Juan Hernandez-Ortiz, Jorge E. Osorio (Colombia-Wisconsin One Health Consortium), Gavin Cloherty (Abbott) et al.
Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2.
N Engl J Med. 2022 Mar 9. doi: 10.1056/NEJMc2201933.
Dr. Yoshihiro Kawaoka (The University of Wisconsin-Madison) et al.
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape
Cell Host Microbe. 2022 Feb 9;30(2):154-162.e5. doi: 10.1016/j.chom.2022.01.005.
Drs. Salim Karim (Centre for the AIDS Programme of Research in South Africa), Penny Moore (National Institute for Communicable Diseases of the National Health Laboratory Service) et al.
SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron
Cell. 2022 Mar 3;185(5):847-859.e11. doi: 10.1016/j.cell.2022.01.015.
Dr. Shane Crotty (La Jolla Institute for Immunology) et al.
Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status
Cell Host Microbe. 2022 Feb 8;S1931-3128(22)00089-0. doi: 10.1016/j.chom.2022.02.003.
Dr. Shane Crotty (La Jolla Institute for Immunology) et al.
Divergent SARS CoV-2 Omicron-reactive T- and B cell responses in COVID-19 vaccine recipients
Sci Immunol. 2022 Feb 3;eabo2202. doi: 10.1126/sciimmunol.abo2202.
Dr. Marion Koopmans and colleagues (Erasmus Medical Center, the Netherlands)
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern
Nat Commun 13, 719 (2022). https://doi.org/10.1038/s41467-022-28354-0
Dr. Johan Neyts et al.
Adipose tissue in COVID-19: detection of SARS-CoV-2 in adipocytes and activation of the interferon-alpha response.
Journal of Endocrinological Investigation. 2022 Feb. DOI: 10.1007/s40618-022-01742-5. PMID: 35169984; PMCID: PMC8852916.
Activation of Type I and Type II Interferon Signaling in SARS-CoV-2-Positive Thyroid Tissue of Patients Dying from COVID-19.
Thyroid : Official Journal of the American Thyroid Association. 2021 Dec;31(12):1766-1775. DOI: 10.1089/thy.2021.0345. PMID: 34541878.
Neutralization against Omicron SARS-CoV-2 from previous non-Omicron infection
Nat Commun 13, 852 (2022). https://doi.org/10.1038/s41467-022-28544-w
Drs. Scott C. Weaver and Pei-Yong Shi (The University of Texas Medical Branch) et al.
Genome-Wide Characterization of SARS-CoV-2 Cytopathogenic Proteins in the Search of Antiviral Targets.
mBio. 2022 Feb 15;13(1):e0016922. doi: 10.1128/mbio.00169-22. Epub ahead of print. PMID: 35164548; PMCID: PMC8844912.
Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries
JAMA Pediatr. Published online January 19, 2022. doi:10.1001/jamapediatrics.2021.6436
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern
Nat Med. 2022 Jan 28. doi: 10.1038/s41591-022-01715-4.
Dr. Ulrike Protzer (Institute of Virology, Technical University of Munich) et al.
Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming
N Engl J Med. 2022 Jan 19. doi: 10.1056/NEJMoa2116747.
Dr. Marion Koopmans (Erasmus University Medical Center, Netherlands) et al.
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection
Nat Immunol. 2022 Jan;23(1):40-49. doi: 10.1038/s41590-021-01089-8.
Dr. Emma Thomson (MRC-University of Glasgow Centre for Virus Research) et al.
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
Nature. 2021 Dec 23. doi: 10.1038/s41586-021-04387-1.
Dr. Penny Moore (National Institute for Communicable Diseases of the National Health Laboratory Service, South Africa) et al.
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study
Clin Microbiol Infect. 2021 Nov 23;S1198-743X(21)00638-8. doi: 10.1016/j.cmi.2021.11.010.
Dr. Linfa Wang (Duke-NUS, Singapore) et al.
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial
The Lancet, December 2, 2021
Alasdair P S Munro, Leila Janani, Victoria Cornelius, Parvinder K Aley, Gavin Babbage, David Baxter, Emma Thompson (University of Glasgow, UK) et al.
Reduced neutralisation of the Delta (B.1.617.2) SARS-CoV-2 variant of concern following vaccination
PLOS Pathogens, December 2, 2021
Chris Davis, Nicola Logan, Grace Tyson, Richard Orton, William Harvey, Massimo Palmarini, Emma Thomson (University of Glasgow, UK) et al.
Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and associated humans in the Netherlands
Nat Commun 12, 6802 (2021). https://doi.org/10.1038/s41467-021-27096-9
Dr. Marion Koopmans (Erasmus Medical Center, Netherlands) et al.
Rapid assessment of SARS-CoV-2 evolved variants using virus-like particles
Science. 2021 Nov 4;eabl6184. doi: 10.1126/science.abl6184.
Dr. Melanie Ott and colleagues (Gladstone Institute of Virology) et al.
Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner
Cell Host Microbe. 2021 Oct 13;29(11):1611-1619.e5. doi: 10.1016/j.chom.2021.10.003.
Dr. Penny Moore (National Institute for Communicable Diseases of the National Health Laboratory Services, South Africa) et al.
Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men
Emerg Microbes Infect. 2021 Oct 28;1-26. doi: 10.1080/22221751.2021.1999777.
Dr. Linfa Wang (Duke-NUS Medical School, Singapore) et al.
A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses
Nat Commun. 2021 Oct 27;12(1):6197. doi: 10.1038/s41467-021-26499-y.
Drs. Florian Krammer, Adolfo García-Sastre, and Peter Palese (Icahn School of Medicine at Mount Sinai)
A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries (nih.gov)
J Infect. 2021 Oct 1. doi: 10.1016/j.jinf.2021.08.049
Dr. Osbourne Quaye/Ghana (West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana) et al.
SARS-CoV-2 infection generates tissue-localized immunological memory in humans
Sci Immunol. 2021 Oct 7;eabl9105. doi: 10.1126/sciimmunol.abl9105.
Drs. Erica Saphire and Shane Crotty (La Jolla Institute for Immunology) et al.
A highly potent antibody effective against SARS-CoV-2 variants of concern
Cell Rep. 2021 Oct 12;37(2):109814. doi: 10.1016/j.celrep.2021.109814.
Dr. Johan Neyts (Rega Institute for Medical Research, University of Leuven) et al.
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
Nat Microbiol. 2021 Oct;6(10):1233-1244. doi: 10.1038/s41564-021-00972-2.
Drs. Pei-Yong Shi (The University of Texas Medical Branch at Galveston) and Matthew Frieman (Institute of Human Virology, University of Maryland) et al.
Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells
Science. 2021 Sep 14;eabj9853. doi: 10.1126/science.abj9853.
Drs. Alessandro Sette, Shane Crotty and Daniela Weiskopf (La Jolla Institute for Immunology) et al.
The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology (Review Article)
Nat Med. 2021 Sep;27(9):1518-1524. doi: 10.1038/s41591-021-01472-w. Epub 2021 Sep 9
Dr. Marion Koopmans (Erasmus MC, the Netherlands) et al.
Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern
Med Microbiol Immunol. 2021 Aug 20 : 1–13. doi: 10.1007/s00430-021-00719-0
Dr. Ulrike Protzer (Institute of Virology, Technical University of Munich) et al.
Heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and BNT162b2
Lancet Infect Dis. 2021 Sep;21(9):1212-1213. doi: 10.1016/S1473-3099(21)00420-5. Epub 2021 Jul 29.
Dr. Ulrike Protzer (Institute of Virology, Technical University of Munich) et al.
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
Cell Rep. 2021 Aug 17;36(7):109530. doi: 10.1016/j.celrep.2021.109530.
Dr. Geoff Falkner (University of Queensland) et al.
Single-amplicon, multiplex real-time RT-PCR with tiled probes to detect SARS-CoV-2 spike mutations associated with variants of concern
J Clin Microbiol. 2021 Aug 25;JCM0144621. doi: 10.1128/JCM.01446-21.
Dr. Raymond Schinazi (Emory University) et al.
Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors
N Engl J Med. 2021 Aug 18. doi: 10.1056/NEJMoa2108453.
Dr. Linfa Wang (Duke-NUS Medical School, Singapore) et al.
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: an interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial
Lancet HIV. 2021 Aug 17;S2352-3018(21)00157-0.
Dr. Penny Moore (National Institute for Communicable Diseases, Johannesburg, South Africa) et al.
BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants
Nature. 2021 Aug;596(7871):273-275. doi: 10.1038/s41586-021-03693-y
Drs. Scott Weaver and Pei-Yong Shi (University of Texas Medical Branch) et al.
Longitudinal analysis of SARS-CoV-2 seroprevalence using multiple serology platforms
iScience DOI: https://doi.org/10.1016/j.isci.2021.102937
Dr. Florian Krammer (Icahn School of Medicine at Mount Sinai, New York) et al.
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
Cell Rep. 2021 Jul 27;36(4):109452.
Drs. Pei-Yong Shi (University of Texas Medical Branch) and Erica Saphire (La Jolla Institute for Immunology) et al.
Understanding why superspreading drives the COVID-19 pandemic but not the H1N1 pandemic
The Lancet Infectious Disease, August 2, 2021
Marion Koopmans (Erasmus University MC, Netherlands) et al.
Translation from bats to humans beyond infectious diseases
Journal of Experimental Medicine, July 27, 2021
Linfa Wang (Duke-NUS, Singapore) et al.
Emergence and spread of a SARS-CoV-2 lineage A variant (A.23.1) with altered spike protein in Uganda
Nat Microbiol. 2021 Jun 23. doi: 10.1038/s41564-021-00933-9.
Dr. Pontiano Kaleebu (Uganda Virus Research Institute) et al.
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
Cell Reports, July 27, 2021
Dr. Alexander Khromykh (University of Queensland, Australia) et al.
Impact of SARS-CoV-2 variants on the total CD4 + and CD8 + T cell reactivity in infected or vaccinated individuals
Cell Rep Med. 2021 Jul 2;100355. doi: 10.1016/j.xcrm.2021.
Drs. Richard H Scheuermann (J. Craig Venter Institute) and Shane Crotty (Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology) et al.
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants
Science. 2021 Jul 1;eabh1766. doi: 10.1126/science.abh1766
Dr. Penny Moore (NHLS Johannesburg National Institute for Communicable Diseases, South Africa) et al.
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
Cell. 2021 Jun 24;184(13):3426-3437.e8. doi: 10.1016/j.cell.2021.04.025.
Dr. Melanie Ott (Gladstone Institute of Virology and Immunology) et al.
Characterization of a new SARS-CoV-2 variant that emerged in Brazil
Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2106535118.
Dr. Yoshihiro Kawaoka (University of Wisconsin-Madison Global Health Institute) et al.
Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans
Nature. 2021 Jun 9. doi: 10.1038/s41586-021-03681-2.
Dr. Florian Krammer (Center for Virology at Icahn School of Medicine at Mount Sinai) et al.
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Science. 2021 May 20;eabh1139. doi: 10.1126/science.abh1139
Dr. Ian Wilson (The Scripps Research Institute) et al.
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters
EBioMedicine. 2021 May 24;68:103403. doi: 10.1016/j.ebiom.2021.103403.
Drs. Rana Abdelnab, Robbert Boudewijns, Caroline S Foo, Lorena Sanchez-Felipe, Xin Zhang, Leen Delang, Suzanne J F Kaptein, Kai Dallmeie and Johan Neyts (Rega Institute for Medical Research, University of Leuven) et al.
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
Nature Communications, June 8, 2021
Alex Khromykh (University of Queensland, Australia) et al.
Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection
Nat Med. 2021 May 17. doi: 10.1038/s41591-021-01377-8
Dr. Kanta Subbarao (The Doherty Institute for Infection and Immunity) et al.
Activate-2: a Double-blind Randomized Trial of BCG Vaccination Against Covid-19 in Individuals at Risk
Medrxiv, May 24, 2021
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
Nature. 2021 Apr 29. doi: 10.1038/s41586-021-03570-8.
Dr. Pardis C Sabeti (Harvard T.H. Chan School of Public Health) et al.
Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics
PNAS, May 2021
GVN Members Dr. Konstantin Chumakov, Christine Benn, Lawrence Blatt, Mihai Netea, and Robert Gallo et al.
Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols
Elife. 2021 Apr 16;10:e65774. doi: 10.7554/eLife.65774.
Dr. Marion Koopmans (Erasmus University Medical Center, Rotterdam, Netherlands) et al.
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics
Nature Biomedical Engineering, May 3, 2021
Dr. Donald Ingber (The Wyss Institute at Harvard, USA) et al.
A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection
Cell Host Microbe. 2021 Apr 15;S1931-3128(21)00181-5. doi: 10.1016/j.chom.2021.04.005.
Dr. Ian Wilson (The Scripps Research Institute) et al.
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
Nature. 2021 Apr 12. doi: 10.1038/s41586-021-03493-4.
Drs. Ulrike Protzer and Andreas Pichlmair (Institute of Virology, Technical University of Munich, Germany) et al.
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
Cell Rep Med. 2021 Mar 16;2(3):100208. doi: 10.1016/j.xcrm.2021.100208
Drs. Florian Krammer (Icahn School of Medicine at Mount Sinai, US) and Amy Chung and Sharon Lewin (Peter Doherty Institute for Infection and Immunity, Australia) et al.
Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study
Lancet Microbe. 2021 Mar 23. doi: 10.1016/S2666-5247(21)00025-2.
Dr. Linfa Wang (DUKE-NUS Medical School) et al.
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
Nature Communications volume 12, Article number: 2037 (2021)
Dr. Amy Chung (Peter Doherty Institute for Infection and Immunity, University of Melbourne Australia) et al.
Pediatric nasal epithelial cells are less permissive to SARS-CoV-2 replication compared to adult cells
Science Direct, March 8, 2021
Dr. Alexander Khromykh (University of Queensland, Australia) et al.
Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2
Science Direct, February 26, 2021
Dr. Alexander Khromykh (University of Queensland, Australia) et al.
Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2
JAMA. 2021 Mar 1;e213341. doi: 10.1001/jama.2021.3341.
Drs. Matthew Frieman and Mohammad Sajadi (Institute of Human Virology, University of Maryland) et al.
Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant
N Engl J Med. 2021 Mar 16. doi: 10.1056/NEJMoa2102214.
Dr. Penny Moore (NHLS Johannesburg National Institute for Communicable Diseases) et al.
TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.
2021 Feb 28;13(3):384. doi: 10.3390/v13030384
Kishimoto M, Uemura K, Sanaki T, Sato A, Hall WW, Kariwa H, Orba Y, Sawa H, Sasaki M.Viruses.
Immunogenicity of prime-boost protein subunit vaccine strategies against SARS-CoV-2 in mice and macaques
Nat Commun. 2021 Mar 3;12(1):1403. doi: 10.1038/s41467-021-21665-8.
Dr. Kanta Subbarao (The Doherty Institute for Infection and Immunity) et al.
Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
mBio. 2021 Feb 16;12(1):e02492-20. doi: 10.1128/mBio.02492-20.
Drs. Florian Krammer and Benhur Lee (Icahn School of Medicine at Mount Sinai) et al.
TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein
Viruses, February 28, 2021, 13(3), 384; https://doi.org/10.3390/v13030384
Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19
mBio. 2021 Feb 9;12(1):e03192-20. doi: 10.1128/mBio.03192-20.
Dr. David Topham (University of Rochester Medical Center) et al.
Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera
Nat Med (2021). https://doi.org/10.1038/s41591-021-01270-4
Dr. Scott Weaver (The University of Texas Medical Branch) et al.
Single Dose Vaccination in Healthcare Workers Previously Infected with SARS-CoV-2
medRxiv. 2021 Feb 1, 2021. https://doi.org/10.1101/2021.01.30.21250843
Matthew B. Frieman, Mohammad M. Sajadi, et al.
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
Cell Rep. 2021 Jan 21;108728. doi: 10.1016/j.celrep.2021.108728
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
Nature. 2021 Jan 25. doi: 10.1038/s41586-021-03237-4.
Drs. Benhur Lee (Icahn School of Medicine at Mount Sinai) and Scott Weaver (University of Texas Medical Branch) et al.
SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike
mBio. 2021 Jan 19;12(1):e02940-20. doi: 10.1128/mBio.02940-20.
Drs. Florian Krammer (Icahn School of Medicine at Mount Sinai) and Yoshihiro Kawaoka (University of Wisconsin-Madison), et al.
Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)
Nat Commun. 2021 Jan 11;12(1):267. doi: 10.1038/s41467-020-20568-4
Dr. Marion Koopmans (Erasmus University Medical Center Rotterdam, Netherlands) et al.
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
Science. 2021 Jan 6;eabf4063. doi: 10.1126/science.abf4063.
Drs. Erica Saphire and Shane Crotty (The La Jolla Virus Network) et al.
The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses
Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30687-30698. doi: 10.1073/pnas.2012939117. Epub 2020 Nov 12
IFN-α2a Therapy in Two Patients with Inborn Errors of TLR3 and IRF3 Infected with SARS-CoV-2
J Clin Immunol. 2021 Jan 3;1-2. doi: 10.1007/s10875-020-00933-0
Marc Lecuit, et al.
Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19
Nat Commun. 2020 Nov 11;11(1):5703. doi: 10.1038/s41467-020-19545-8.
Kanta Subbarao and Amy Chung, et al.
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
PLOS Biology, November 6, 2020 https://doi.org/10.1371/journal.pbio.3000970
Jae Jung, et al.
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
Cell. 2020 Oct 20, doi: 10.1016/j.cell.2020.10.028B
Benhur Lee, e.t al
Host-directed editing of the SARS-CoV-2 genome
Biochemical and Biophysical Research Communications, 5 November 2020
William Hall, et al.
SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination
Adv Mater. 2020 Oct 28;e2005637. doi: 10.1002/adma.202005637.
Dr. Luis Martinez-Sobrido (University of Rochester Medical Center), et al.
Baricitinib treatment resolves lower airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
Cell, November 09, 2020 DOI:https://doi.org/10.1016/j.cell.2020.11.007
Raymond Schinazi et al.
Benchmarking evolutionary tinkering underlying human–viral molecular mimicry shows multiple host pulmonary–arterial peptides mimicked by SARS-CoV-2
Cell Death Discov. 2020; 6: 96. Published online 2020 Oct 2. doi: 10.1038/s41420-020-00321-y
George M. Church et al.
Evidence that coronavirus superspreading is fat-tailed
PNAS first published November 2, 2020; https://doi.org/10.1073/pnas.2018490117
James Collins et al.
Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses
Alexander Bukreyev
Antiviral Res. 2020 Oct; 182: 104874. Published online 2020 Jul 28. doi: 10.1016/j.antiviral.2020.104874
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity
Cell, Volume 183, ISSUE 4, P996-1012.e19, November 12, 2020
Katheryn Hastie, Erica Ollmann Saphire et al.
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Open Forum Infectious Diseases. Accepted Oct 2020
Repeat COVID-19 Molecular Testing: Correlation of SARS-CoV-2 Culture with Molecular Assays and Cycle Thresholds
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Marion Koopmans (Erasmus MC), Yazdan Yazdanpanah (REACTING)
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Dr. Raymond Schinazi (Emory University)
The Origin of COVID-19 and Why It Matters
The American Journal of Tropical Medicine and Hygiene, Volume 103, Issue 3, 2 Sep 2020, p. 955 – 959
William DeLuc (University of Texas Medical Branch) and Peter Doherty (Doherty Institute)
Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine
N Engl J Med. 2020 Sep 2. doi: 10.1056/NEJMoa2026920
Dr. Matthew Frieman (Institute of Human Virology, University of Maryland)
A genetic barcode of SARS-CoV-2 for monitoring global distribution of different clades during the COVID-19 pandemic
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Dr. William Hall (University College Dublin, Ireland)
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Dr. Albert Osterhaus (University of Hannover, Germany)
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Dr. Pontiano Kaleebu (Uganda Virus Research Institute)
Evaluation of serological tests for SARS-CoV-2: Implications for serology testing in a low-prevalence setting
J Infect Dis. 2020 Aug 6;jiaa467. doi: 10.1093/infdis/jiaa467
Drs. Damian Purcell, Sharon Lewin, and Kanta Subbarao (The Doherty Institute for Infection and Immunity) has validated five different point-of-care (PoCT)
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Co-author Raymond Schinazi (Emory University, USA), Clinical Infectious Diseases, June 2020
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Co-author Raymond Schinazi (Emory University, USA), medRxiv, May 2020
Phenotype and Kinetics of SARS-CoV-2-specific T Cells in COVID-19 Patients with Acute Respiratory Distress Syndrome
Marion Koopmans (Erasmus University Medical Center, Rotterdam, Netherlands)
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Co-Authors Scott Weaver (UTMB, USA) and Robert Garry (Tulane, USA)
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George Church (The Wyss Institute at Harvard, USA)
Nat Biotechnol. 2020; 10.1038/s41587-020-0577-1.
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Co-Authors Konstantin Chumakov (Food and Drug Administration, USA) and Robert Gallo (IHV, University of Maryland School of Medicine, USA)
Science, June 12, 2020
Cross-reactive Antibody Response Between SARS-CoV-2 and SARS-CoV Infections
Ian Wilson (The Scripps Research Institute, La Jolla, CA, USA)
Cell Rep, June 2, 2020
COVID-19 and SARS Coronavirus 2: Antibodies for the Immediate Rescue and Recovery Phase
Ramesh Akkina (Colorado State University, USA)
Front. Immunol., May 29, 2020
Validation and verification of the Abbott RealTime SARS-CoV-2 assay analytical and clinical performance
Journal of Clinical Virology, August 2020
Stat 2 signaling a double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters
Johan Neyts (KU Leuven, Belgium)
bioRxiv, April 2020
Detection of Recombinant Rousettus Bat Coronavirus GCCDC1 in Lesser Dawn Bats (Eonycteris spelaea) in Singapore
Linfa Wang (Duke-NUS, Singapore)
Viruses, May 2020
A serological assay to detect SARS-CoV-2 seroconversion in humans.
Florian Krammer (Center for Virology at Icahn School of Medicine at Mount Sinai, USA)
Nature Medicine, May 2020
An Infectious cDNA Clone of SARS-CoV-2
Co-Authors James LeDuc and Scott Weaver (University of Texas Medical Branch, Galveston, TX, USA)
Cell Host Microbe, April 13, 2020
Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model
Marion Koopmans (Erasmus University Medical Center, Rotterdam, Netherlands)
Science, April 17, 2020